Short term variability of single breath carbon monoxide transfer factor.

Variability of the single-breath carbon monoxide transfer factor as a function of inspired oxygen pressure.

We measured single-breath CO transfer factor (TLCO) and alveolar oxygen partial pressure (PAO2) six times at each of three fractions of inspired oxygen (FIO2) (0.17, 0.21, 0.26) in twelve healthy subjects, to determine whether one FIO2 would have the advantage of producing less variable TLCO results than the others. Measured TLCO was adjusted for the increase in carboxyhaemoglobin during the te...

Single breath transfer factor measured concurrently by two methods in asthmatic and normal subjects.

Haydu, S. P. (1974). Thorax, 29,232-236. Single breath transfer factor measured concurrently by two methods in asthmatic and normal subjects. There have been conflicting reports that the single breath transfer factor for carbon monoxide in asthma may be normal, high or low. To resolve this point the single breath transfer factor was measured in comparable groups of asthmatic and normal subjects...

Single breath carbon monoxide diffusing capacity (transfer factor)

Reference values for lung function tests. III. Carbon monoxide diffusing capacity (transfer factor).

Carbon monoxide diffusing capacity (DLCO) or transfer factor (TLCO) is a particularly useful test of the appropriateness of gas exchange across the lung alveolocapillary membrane. With the purpose of establishing predictive equations for DLCO using a non-smoking sample of the adult Brazilian population, we prospectively evaluated 100 subjects (50 males and 50 females aged 20 to 80 years), rando...

Clinical assessment of a rebreathing method for measuring pulmonary gas transfer.

A rebreathing method for measuring carbon monoxide transfer factor (TLCO) and transfer coefficient (KCO) is evaluated. The test was performed on 42 subjects. Seventeen of these had normal lung function while the remainder suffered from various conditions, most having fibrosing alveolitis. No patients with severe airways obstruction were included in the group. The results were compared with sing...